Suprarenal glands, also called adrenal glands, are triangular glands located on top of both kidneys. These glands produce hormones which help to regulate body’s immune system, blood pressure, and other essential homeostasis functions. Adrenal cortical hormones, also termed as steroid hormones, are polycyclic molecules that are produced in the adrenal gland by adrenal cortex located in its outer region. Adrenal cortical hormones are structurally similar to cholesterol and play a crucial role in regulating body’s response to physical injury, physiological stress, infection, chemical imbalances, and other functions in the body. Based on function, these hormones are categorized into three classes: androgens, mineralocorticoids, and glucocorticoids. Androgens, also called sex hormones, are responsible for promotion and maturation of human reproductive organs. Glucocorticoids process carbohydrates and fats, while mineralocorticoids are responsible for maintaining electrolyte concentration in the body.
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Adrenal glands can cause serious health issues by either increasing production of certain hormones or producing too little. This leads to hormonal imbalances in human body. These anomalies of the adrenal glands functioning can be caused by numerous diseases/disorders of the pituitary gland or adrenal glands. Disorders due to adrenal deficiency is one of the most common disease that occurs worldwide. Adrenal deficiency might result in severe abdominal pain, depression, extremely low blood pressure, muscle weakness, weight loss, and others. Adrenal deficiency occurs primarily due to impairment of adrenal glands, pituitary glands, or the hypothalamus. It has been estimated that globally out of 100,000 people, one to four individuals is affected with Addison’s disease in all the age groups and the sexes. Additionally, nearly one in 10,000 people is affected by Addison’s disease in the U.K. Hence, increasing incidence of people suffering from adrenal deficiency due to changing lifestyle is a major driver of the adrenal cortical hormones and derivatives market. However, rise in cost of treatment, side effects in some of the treatments, are lack of reimbursement policies in developing countries are factors hampering the growth of the global adrenal cortical hormones and derivatives market.
Various disorders such as Cushing’s syndrome, Addison’s disease, and others are caused due to imbalance of these hormones. Several screening tests such as ACTH stimulation test and CRH stimulation test are performed to check adrenal deficiency. Similarly, ultrasound or X-ray test of abdomen is performed to detect the presence of calcium deposition which may indicate signs of bleeding in adrenal gland or tuberculosis. Several medications such as replacement corticoids are available for the treatment of adrenal deficiency.
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The global adrenal cortical hormones and derivatives market can be segmented based on type of disorder and end-user. In terms of type of disorder, the market can be classified into Cushing’s syndrome, Addison’s disease, and others. Based on end-user, the global adrenal cortical hormones and derivatives market can be segmented into hospitals, diagnostic centers, academic & research institutes, and others.
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Geographically, the global adrenal cortical hormones and derivatives market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America holds a major share of the market due factors such as presence of key players, technological advancements in the region, well-established health care infrastructure with reimbursement policies. The adrenal cortical hormones and derivatives market in Asia Pacific is expected to grow rapidly in the next few years due to increase in geriatric population, investments by key industries, and government initiatives to invest in health care.
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Key players in the global adrenal cortical hormones and derivatives market are Pfizer, Inc. Novartis International AG, Sanofi, Boehringer Ingelheim, Bristol-Myers Squibb, Teva Pharmaceutical Industries Ltd., Eli Lilly and Company, GlaxoSmithKline plc, Merck & Co., Inc., and AbbVie, Inc.
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